Headlines Alzheimer brain damage 'reversed'


Scientists have reversed the damage caused to the brain by Alzheimer's disease during tests on mice.

The US team used an antibody to remove the build up of potentially damaging deposits from the area of the brain responsible for memory and cognition.

The treatment reversed the nerve cell damage in days, Washington University School of Medicine researchers said.

UK experts described the findings, published in the Journal of Clinical Investigation, as "exciting".

Prior to the study, it was thought that once the damage had been caused to the brain there was no way of repairing it.

Lead author Robert Brendza said: "We thought that clearing the plaques (deposits) would halt the progression of the damage.

"But what we saw was much more striking - in just three days there were 20 to 25% reductions in the number or six of the existing swellings."

He said more research was needed to see if the effects could be repeated in humans with the degenerative brain disorder for which there is no cure.

It is estimated that 2% to 5% of people over 65 years of age and up to 20% of those over 85 years of age have Alzheimer's.

The cause of the disease is not known although people with Alzheimer's do have a build up of abeta, a glycoprotein, which could be responsible for the nerve cell damage.

Mice with a build up of abeta were injected with the antibody and then using a dye to give detailed images of the nerve cell branches, the team were able to monitor the improvement over a few days.

This is pretty cool. Maybe in a few years, we'll be able to medicate alzheimers patients well enough to keep their memories intact.

I sincerly hope we can find a cure for this. Watching my grandmother die of Alzheimer's when I was in grade 4 was horrible. It utterly crushed my father when she couldn't even recognize her own son. I was pretty young, and it wasn't even having my grandmother not know who I was, it was watching my dad while he was destroyed by this that hurt me the most. Worst disease ever. No one should have to see their mother forget their total existance.


~Broken Angel~
Wow...isnt it amazing that modern science these days is coming up with cures for everything?


Yay fire!
sinamon said:
Wow...isnt it amazing that modern science these days is coming up with cures for everything?
Indeed. Medicine has come a LONG way since using leeches and "anesthetizing" patients with liquor for surgeries.


How dare you!?
That is awesome. Thats something that shouldnt be taken away from anyone. A memory is something personal that belongs to the beholder. To lose that is truely sad..
I really hope that this research comes threw with a cure, or atleast something that helps.